Sophos support indicates the permissions need to be Allowed manually and they don't support deployment with Jamf Pro. We reviewed the config profile and ensured it has the boolean values required (as someone outside of Sophos discovered in the comments). We have been deploying a config profile for some time now with the System Extensions + PPPC requirements based on this article: I wanted to post here to see - has anyone experienced and/or mitigated this issue? We also have had to exclude new Monterey systems from our Sophos policy, as it was causing freezing right after policy completion. We have narrowed the issue down to Sophos, as when we uninstall in Safe mode, the issue is resolved. Recently, we've had an uptick in customers reporting their Intel Monterey systems are unusable for about 30-45 min, then they function normally. We have been deploying Sophos via Jamf Pro for years now.
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